WP4 Intervention & Product development
Intervention (in-vitro and in-vivo) & Product development
- What's its about?
In WP4, Shift2Health combines advanced laboratory research with practical food interventions to explore and counteract the effects of chronodisruption on obesity. - Intervention - in vitro
- Identify novel biomarkers for obesity during chronodisruption
- RNA sequencing
- to study loss or shifts in the rhythmic gut transcriptome
- Organ-on-a-chip based barrier integrity assays to determine
- intestinal rhythmicity disruptions
- identification of microbial metabolites
- chronobiotics that affect rhythmicity in gut epithelial homeostasis during chronodisruption
- Intervention - in vivo
Food Intervention study in shift workers → See the graphic below for a visual summary.